NCT03445078

Correction of Selenium Deficiency Has Effect on Thyroid Function

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Peking Union Medical College Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Previous literature has found potential association between selenium deficiency and inactivated glutathione peroxidase and deiodinase, which may contribute to subsequent elevation of T4 and ratio of T4/T3. Conduction of a case-control study (ID: Liuyanping3) has been applied on Clinicaltrials.gov to further elucidate effect of selenium deficiency on thyroid function. Based on its data, the investigators will perform a randomized, placebo-controlled,single-blinded crossover study on 20 participants with selenium deficiency to verify health consequence of selenium.

Conditions

• Selenium Deficiency

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	selenium supplementation	administration of selenium-rich corn powder 20g/d offering selenium 100μg/d
DIETARY_SUPPLEMENT	ordinary corn powder	ordinary corn powder,20g/d(selenium contain \<0.5ug/20g).

Timeline

• Start date: 2018-09-01
• Primary completion: 2018-12-01
• Completion: 2019-04-01
• First posted: 2018-02-26
• Last updated: 2018-05-31