Trials / Completed
CompletedNCT03444519
The Therapeutic Time Window of Mannitol During Craniotomy for Optimal Brain Relaxation in Patients With Supratentorial Tumours
Brain Relaxation Facilitated by Mannitol in Craniotomy: Insight Into the Optimized Operation Window
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 100 (actual)
- Sponsor
- Huashan Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 60 Years
- Healthy volunteers
- Not accepted
Summary
Although mannitol is used for brain relaxation during neurosurgery and in the treatment of raised intracranial pressure; there is not a consensus on its safe, effective dose and the duration of its administration. This study aimed to compare the effects of the mannitol in different use times, on the brain relaxation, electrolyte, lactate levels of the blood, peroperative fluid balance and the volume of the urine in supratentorial mass resection surgeries.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Mannitol | This drug is in our routine use of neuroanesthesia, are given for facilitate brain relaxation |
Timeline
- Start date
- 2018-03-01
- Primary completion
- 2019-03-14
- Completion
- 2019-04-01
- First posted
- 2018-02-23
- Last updated
- 2020-11-20
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT03444519. Inclusion in this directory is not an endorsement.