NCT03443037

Benefits of Amantadine in Patients With Coma State

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 56 (estimated)
• Sponsor: Dokuz Eylul University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The study was a single center observational-prospective study and approved by local ethics committee. Patients in coma state due to traumatic brain injury, cardiac arrest or ischemic stroke who are older than 18 years of age were included in the study. Patients who received amantadine 200mg/day for fourteen days according to ICU protocols decided by primary physician formed the amantadine group, and the rest of the subjects were included in the control group. All patients were evaluated for Glasgow Coma Score, JFK Coma Recovery Scale and Disability Rating Scale once a week for three months.

Conditions

• Coma; Prolonged
• Amantadine

Interventions

Type	Name	Description
DRUG	amantadine sulphate

Timeline

• Start date: 2016-03-01
• Primary completion: 2019-07-01
• Completion: 2019-07-01
• First posted: 2018-02-22
• Last updated: 2018-09-06

Locations

1 site across 1 country: Turkey (Türkiye)

Regulatory

• FDA-regulated drug study