NCT03433144

The Effects of Tranexamic Acid on Blood Loss During Orthognathic Surgery

• Status: Withdrawn
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Nick Emanuele · Academic / Other
• Sex: All
• Age: 16 Years – 65 Years
• Healthy volunteers: Accepted

Summary

This study seeks to answer the question: Does a single pre-operative dose of tranexamic acid have a statistically significant reduction in blood loss during orthognathic surgery? If it does, this drug may begin to be used routinely during orthognathic surgery to reduce blood loss in our patients.

Conditions

• Tranexamic Acid
• Orthognathic Surgery

Interventions

Type	Name	Description
DRUG	Tranexamic Acid Injectable Solution	the drug will be given to patients intravenously at a dose of 10mg/kg pre-operatively after induction on general anesthesia
OTHER	Placebo (normal saline 0.9%)	An equivalent amount of normal saline (0.9%) will be given to the patient pre-operatively after induction of general anesthesia. The amount of saline given will correspond to the same amount of fluid which would have been given had the patient been in the intervention group.

Timeline

• Start date: 2018-06-01
• Primary completion: 2019-02-01
• Completion: 2020-07-06
• First posted: 2018-02-14
• Last updated: 2021-08-06

Locations

1 site across 1 country: Canada