Clinical Trials Directory

Trials / Completed

CompletedNCT03433027

A Study of BB-401 in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

A Phase 2 Trial of Intratumoral EGFR Antisense DNA (BB-401) in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (HNSCC) Who Have Failed All Available Standard Therapies

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
16 (actual)
Sponsor
Benitec Biopharma, Inc. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the safety, tolerability and efficacy of intratumoral injections with an Epidermal Growth Factor Receptor (EGFR) AntiSense DNA (BB-401) in patients with metastatic/recurrent HNSCC.

Conditions

Interventions

TypeNameDescription
DRUGBB-401BB-401 1.92ug/mL Intratumoral Injections, every week for up to 8 weeks

Timeline

Start date
2018-03-15
Primary completion
2018-12-12
Completion
2020-04-06
First posted
2018-02-14
Last updated
2020-04-15

Locations

6 sites across 2 countries: Australia, Russia

Source: ClinicalTrials.gov record NCT03433027. Inclusion in this directory is not an endorsement.