Trials / Active Not Recruiting
Active Not RecruitingNCT03432806
A Study of Imaging, Blood, and Tissue Samples to Guide Treatment of Colon Cancer and Related Liver Tumors
Development of Novel Imaging and Laboratory Biomarkers to Monitor the Liver Pre-metastatic Niche and Guide Treatment of Colon Cancer: A Pilot Study
- Status
- Active Not Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 51 (actual)
- Sponsor
- Memorial Sloan Kettering Cancer Center · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to explore novel ways of diagnosing colon cancer and predicting its propensity to spread to other organs such as the liver.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | blood draws | Patients will have 10 mL of peripheral venous blood drawn immediately prior to surgery, in the post anesthesia care unit (PACU), and at the first postoperative clinic visit for a total of 30 mL. |
| PROCEDURE | colectomy or hepatectomy | Three small pieces of otherwise "normal-appearing" liver of 0.5-1 cm3 collected intraoperatively from patients in all four groups (including Group D). Because liver biopsy is less frequently performed during operations for benign colon lesions or Stage I-III colon cancers, this single aspect of the protocol can be made optional at the discretion of the surgical attending or the patient, however bloods and tissue from pathology will still be collected. |
| DIAGNOSTIC_TEST | Fibroscan test | This may be done either at a preoperative clinic setting or immediately prior to surgery. |
Timeline
- Start date
- 2017-11-28
- Primary completion
- 2026-11-01
- Completion
- 2026-11-01
- First posted
- 2018-02-14
- Last updated
- 2025-12-02
Locations
4 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT03432806. Inclusion in this directory is not an endorsement.