Clinical Trials Directory

Trials / Unknown

UnknownNCT03428971

P-wave Terminal Force in Patients With Atrial Fibrillation.

P-wave Terminal Force in Patients With Atrial Fibrillation: Can we Predict Number of Hospitalisations and Left Atrial Electrical Remodelling? - Ptf-AF Trial

Status
Unknown
Phase
Study type
Observational
Enrollment
600 (estimated)
Sponsor
Medical University of Lublin · Academic / Other
Sex
All
Age
18 Years – 90 Years
Healthy volunteers
Not accepted

Summary

It is suggested that P-wave terminal force (Ptf), a product of the amplitude (PAM) and the duration (PT) of the terminal phase of P-wave in lead V1, shows early delay in left atrial conduction, observed earlier that the dilatation of left atrium. The aim is to follow PT, PAM and Ptf changes during 5-year follow-up (5FU) and examine the relation of these changes to the number of AF episodes requiring hospitalisation (HOSP) for restoration of sinus rhythm (RSR).

Detailed description

Background. It is suggested that P-wave terminal force (Ptf), a product of the amplitude (PAM) and the duration (PT) of the terminal phase of P-wave in lead V1, shows early delay in left atrial conduction, observed earlier that the dilatation of left atrium. Aim. We aim to follow PT, PAM and Ptf changes during 5-year follow-up (5FU) and examine the relation of these changes to the number of AF episodes requiring hospitalisation (HOSP) for restoration of sinus rhythm (RSR). We hypothesise that, in patients with atrial fibrillation (AF): 1. the index parameters (PT, PAM, Ptf), characterising left atrial repolarization, correlates the number of future hospitalisations (HOSP) aimed for restoration of sinus rhythm (RSR) in 5-year follow-up (5FU) 2. in 5FU the number of HOSP aimed for RSR correlates with the progression of left atrium electrical remodelling, expressed as PAM5,PT5, Ptf5 at 5FU.

Conditions

Interventions

TypeNameDescription
PROCEDUREcardioversionDirect current (DC) cardioversion for sinus rhythm restoration

Timeline

Start date
2018-03-01
Primary completion
2020-03-07
Completion
2020-12-07
First posted
2018-02-12
Last updated
2020-01-22

Locations

1 site across 1 country: Poland

Source: ClinicalTrials.gov record NCT03428971. Inclusion in this directory is not an endorsement.