Trials / Completed
CompletedNCT03426462
Time to Peak Effect of Propofol in Children
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 48 (actual)
- Sponsor
- University Hospital, Basel, Switzerland · Academic / Other
- Sex
- All
- Age
- 1 Year – 13 Years
- Healthy volunteers
- Accepted
Summary
In order to determine the speed of onset of the anaesthetic propofol in children, investigators will compare the two age groups 1-6 years vs 8-13 years. The primary outcome measure is the time to peak effect of a bolus of proposal, which is measured by analysing the electroencephalogram by using the permutation entropy. Further pharmacodynamic modelling will enable investigators to quantify the difference with age in the hypnotic effect of propofol.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Propofol | Induction of anesthesia and two further deepening episodes will be performed whilst recording the electroencephalogram. |
Timeline
- Start date
- 2018-04-23
- Primary completion
- 2018-12-04
- Completion
- 2018-12-04
- First posted
- 2018-02-08
- Last updated
- 2019-01-30
Locations
1 site across 1 country: Switzerland
Source: ClinicalTrials.gov record NCT03426462. Inclusion in this directory is not an endorsement.