NCT03425448

Neutrolin Versus Heparin for Locking Hemodialysis Catheters

Neutrolin Versus Heparin for Locking Hemodialysis Catheters: A Multi-center, Double-Blind, Randomized Controlled Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 192 (estimated)
• Sponsor: King Abdullah International Medical Research Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Hemodialysis catheter related bacterial infections represent a major cause of mortality and morbidity in the hemodialysis population. Several locking agents had been tried with variable degree of success but not without side effects. Neutrolin catheter locking agent comprises of heparin,citrate and trauolidine that had been studied in a prospective study in Germany, and it demonstrated a very good result in terms of reducing the catheter related infections and thrombosis. This study is a multi-center, double-blind RCT comparing the hemodialysis catheter locking solution Neutrolin with heparin in reducing the rate of catheter related bacterial infection and thrombosis.

Conditions

• Hemodialysis Catheter Infection
• Catheter Thrombosis

Interventions

Type	Name	Description
DRUG	Heparin	Heparin hemodialysis catheter lock solution
DEVICE	Neutrolin	Neutrolin hemodialysis catheter lock

Timeline

• Start date: 2019-04-04
• Primary completion: 2020-10-04
• Completion: 2021-04-04
• First posted: 2018-02-07
• Last updated: 2019-03-05