Trials / Unknown
UnknownNCT03424616
Deep Brain Stimulation of Nucleus Accumbens for Opioid Relapse Prevention
Deep Brain Stimulation of Nucleus Accumbens for Opioid Relapse Prevention:A Multicenter Randomized Double-Blind Sham-stimulation Controlled Clinical Trial
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- Sponsor
- Tang-Du Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 50 Years
- Healthy volunteers
- Not accepted
Summary
Nucleus accumbens plays important roles in the process of opiate addiction and initial of relapse after detoxification.According to the single-centered preliminary open-labeled prospective trial results, the investigators hypothesize that bilateral stimulation of the NAc will effectively reduce the relapse of the opiate dependence.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | Suzhou Sceneray® DBS System | We plan to use the SceneRay 1242 (SceneRay, SuZhou, China) electrode with a diameter of 1.27 mm and 4 contacts. The SceneRay 1242 electrode combined with the SceneRay 1181 implantable pulse generator has the advantage of adaptive coverage area for the Ventral Capsule/Ventral Striatum, enabling simultaneous implantation in the nucleus accumbens (NAc; 2 ventral contacts) and the anterior limb of the internal capsule (ALIC; 2 dorsal contacts) with independently programmed parameters such as frequency, amplitude, and voltage; and remote and wireless programing, which allows for convenient and prompt adjustments in emergency situations. |
Timeline
- Start date
- 2018-02-06
- Primary completion
- 2020-01-30
- Completion
- 2020-01-30
- First posted
- 2018-02-07
- Last updated
- 2018-02-07
Locations
5 sites across 1 country: China
Source: ClinicalTrials.gov record NCT03424616. Inclusion in this directory is not an endorsement.