NCT03424187

The Acute Effects of Food Structure on Post Prandial Glucose and Subsequent Metabolic Responses

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 15 (actual)
• Sponsor: Imperial College London · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

Aims: To investigate the effects of different food structures on glucose concentrations and subsequent metabolic responses including insulin,GIP, GLP-1 DESIGN: A randomised, controlled, clinical trial.

Detailed description

Rationale: There is very little evidence at the present time in the role of food structure in glucose homeostasis. There is circumstantial evidence that foods consumed intact have great effects on suppressing appetite. To test the effect of three structurally different meals with the same nutritional content and volume on appetite regulation. Each participant will receive the following meals: Solid meal group. Milled (intact-cell) meal group. Milled (destroyed-cell) meal group. All of which will contain the same macro and micro nutrients from the same food sources

Conditions

• Obesity

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	chickpea	all three meals are isocaloric but different in the chickpea structure( physical form): • Whole chickpea, flour chickpea, intact cell flour chickpea

Timeline

• Start date: 2016-07-01
• Primary completion: 2017-05-01
• Completion: 2018-07-01
• First posted: 2018-02-06
• Last updated: 2021-04-02
• Results posted: 2021-04-02