Trials / Withdrawn
WithdrawnNCT03421678
Ethnic/Racial Differences in Metabolism and DNA Adduct Formation
Ethnic/Racial Differences in Metabolism and DNA Adduct Formation by 1,3-butadiene
- Status
- Withdrawn
- Phase
- —
- Study type
- Observational
- Enrollment
- 0 (actual)
- Sponsor
- Masonic Cancer Center, University of Minnesota · Academic / Other
- Sex
- All
- Age
- 21 Years
- Healthy volunteers
- Accepted
Summary
The study will investigate the role of 1,3-butadiene metabolic activation and deactivation in lung cancer risk among various ethnic/racial groups. This project will require urine samples from smokers and nonsmokers from the three ethnic/racial groups recruited by the Clinical and Biomarker Core for the analysis of 1,3-butadiene DNA adducts. Data on nicotine intake (urinary TNE) in these subjects as well as in 400 lung cancer cases and 400 controls from Project 1 will be also required for this project.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | Urine Sample | One to two home visits where tobacco use and medical history and biological samples will be collected including blood, buccal cells and urine |
Timeline
- Start date
- 2020-10-01
- Primary completion
- 2023-06-01
- Completion
- 2023-06-01
- First posted
- 2018-02-05
- Last updated
- 2020-10-05
Source: ClinicalTrials.gov record NCT03421678. Inclusion in this directory is not an endorsement.