NCT03419052

MINDSpeed Food and Brain Training RCT

MIND Food and Speed of Processing Training in Older Adults With Low Education, The MINDSpeed Alzheimer's Disease Prevention Pilot Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 212 (actual)
• Sponsor: Indiana University · Academic / Other
• Sex: All
• Age: 60 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to learn how foods high in polyphenols and brain training exercises affect older adults' cognitive performance

Detailed description

Adults with low education who give informed consent will complete a baseline cognitive assessment and then be randomized to one of four arms: 1) MIND foods and cognitive training, 2) MIND foods and control training, 3) control foods and cognitive training, or 4) control foods and control training. All interventions are conducted through applications running on a tablet computer device that we will provide to all participants for the study duration. Cognitive training is delivered through the online BrainHQ program from Posit Science, Inc. The foods will be shown on the tablet device in an online shopping format. Selected foods will be prepared and delivered by the study team. Active intervention will last for 12 weeks. After the 12-weeks, free food deliveries will cease but participants who were allocated to cognitive training will continue to have access to BrainHQ. Those in the MIND food arms will be encouraged to maintain MIND food consumption.

Conditions

• Low Education
• Cognition
• Cognitive Training
• Polyphenols

Interventions

Type	Name	Description
BEHAVIORAL	Speed of processing training	Speed of processing training is provided by the Internet-based BrainHQ program from Posit Science, Inc. BrainHQ contains five different speed training modules (Hawk Eye, Visual Sweeps, Fine Tuning, Eye for Detail, Sound Sweeps) which tap time-order judgment, visual discrimination, spatial-match, forward-span, instruction-following, and memory.
BEHAVIORAL	MIND foods	The "MIND" diet (created by the Rush Aging \& Memory group) specifically emphasizes foods high in polyphenols such as berries, nuts, cocoa, black beans, olive oil, and green leafy vegetables. Participants select these foods from the digital study application and receive them through home delivery.
BEHAVIORAL	Cognitive training control	Control training is provided by the Internet-based BrainHQ program from Posit Science, Inc.These are inert games such as tic-tac-toe, connect 4, battleship, etc.
BEHAVIORAL	Control foods	Foods contain low polyphenols. Participants select these foods from the digital study application and receive them through home delivery.

Timeline

• Start date: 2019-01-10
• Primary completion: 2024-03-08
• Completion: 2024-03-08
• First posted: 2018-02-01
• Last updated: 2025-03-07
• Results posted: 2025-03-07

Locations

1 site across 1 country: United States