NCT03418714

Effects of Salvinorin A on Brain Function

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 13 (actual)
• Sponsor: Johns Hopkins University · Academic / Other
• Sex: All
• Age: 21 Years – 50 Years
• Healthy volunteers: Accepted

Summary

This study will investigate the effects of salvinorin A on human brain activity and connectivity using functional magnetic resonance imaging (fMRI) methods. An inhalation route of administration will be used as it is the most common route for contemporary use of Salvia divinorum, a plant containing salvinorin A.

Detailed description

Volunteers will undergo two experimental sessions that include the inhalation of salvinorin A. The first session will be completed in a comfortable space furnished as a living room, and the second session will be conducted within a magnetic resonance imaging (MRI) scanner.

Conditions

• Drug Effect

Interventions

Type	Name	Description
DRUG	Salvinorin A	Salvinorin A, blinded doses

Timeline

• Start date: 2017-12-14
• Primary completion: 2020-03-02
• Completion: 2020-03-02
• First posted: 2018-02-01
• Last updated: 2021-03-04
• Results posted: 2021-03-04

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study