NCT03418467

Risk Factors in Tachycardiomyopathy

Evaluation of Risk Factors for Therapeutic Outcome in Patients with Tachycardiomyopathy

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 60 (estimated)
• Sponsor: University Hospital Tuebingen · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Decision between rate control and rhythm control can be a challenge in clinical practice. While there is some guiding evidence, we still lack a comprehensive insight into different subgroups of patients that will benefit from a rhythm control treatment. EMPATHY is a prospective clinical study in patients presenting with heart failure and a tachyarrhythmic rhythm disturbance. Biomarkers, routinely obtained results from clinical examinations, and results from endomyocardial biopsies shall be evaluated to identify patients which have better outcome from a rhythm control strategy by ablation therapy or, if contraindicated by pharmacological rhythm control. This study is designed to identifying risk factors and subgroups profiting from rhythm restoration and therefore improve current therapeutic approaches and the rate of recurrence-free survival.

Conditions

• Atrial Fibrillation
• Atrial Flutter
• Ventricular Premature Complexes

Timeline

• Start date: 2018-10-11
• Primary completion: 2025-01-31
• Completion: 2030-05-01
• First posted: 2018-02-01
• Last updated: 2025-03-28

Locations

1 site across 1 country: Germany