Clinical Trials Directory

Trials / Completed

CompletedNCT03417011

FORWARD PRO Study Interventional Post-market Study With the Evolut™ PRO System

Status
Completed
Phase
Study type
Observational
Enrollment
638 (actual)
Sponsor
Medtronic Cardiovascular · Industry
Sex
All
Age
Healthy volunteers
Not accepted

Summary

Prospective, single-arm, multi-center, interventional post-market study. After signing informed consent, eligible subjects will be implanted with the CE marked Evolut™ PRO system. The investigation purpose is to evaluate the acute and long term clinical performance and safety of Evolut™ PRO in a routine hospital setting in patients with symptomatic native aortic valve stenosis or a stenosed, insufficient, or combined surgical bioprosthetic valve failure necessitating valve replacement within the approved intended use in local geography.

Detailed description

Approximately 600 subjects implanted with the Evolut™ PRO at up to 40 sites in Europe. Other regions may be added depending on the regulatory status of the device.

Conditions

Interventions

TypeNameDescription
DEVICEMedtronic CoreValve™ Evolut™ PRO System (Evolut™ PRO System)Transcatheter Aortic Valve Replacement with Medtronic Evolut PRO system

Timeline

Start date
2018-02-26
Primary completion
2019-03-06
Completion
2024-02-26
First posted
2018-01-31
Last updated
2025-09-09

Locations

39 sites across 14 countries: Austria, Belgium, Denmark, Finland, France, Germany, Israel, Italy, Netherlands, Norway, Slovenia, Spain, Switzerland, United Kingdom

Source: ClinicalTrials.gov record NCT03417011. Inclusion in this directory is not an endorsement.