NCT03416959

Bone Metastases Database of Patients Treated Surgically for Impending or Pathologic Fracture of Long Bones

Prospective Bone Metastases Database

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 120 (estimated)
• Sponsor: Istituto Ortopedico Rizzoli · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The aims of this study are to collect prospective data on the natural history of bone metastases (BMs) and skeleta related events (SREs),

Detailed description

The aims of this study are to evaluate clinical and biological factors of patients with BMs after reconstruction with intramedullary fixation (IMN) or endoprosthetic reconstruction (EPR) with a specific focus on (1) the rate of complication or failure; (2) differences in complication rates by anatomic site; (3) functional results as assessed by the Musculoskeletal Tumor Society System (MSTS); (4) differences in complication rate between patients treated with INM versus EPR; and (5) differences in survival in patients with metastatic bone disease based on disease-specific, laboratory, and demographic information.

Conditions

• Neoplasm Metastasis

Interventions

Type	Name	Description
PROCEDURE	intramedullary fixation or endoprosthetic reconstruction	Surgical treatment for long bone metastases with intramedullary nail or endoprosthetic reconstruction

Timeline

• Start date: 2018-01-01
• Primary completion: 2027-12-31
• Completion: 2027-12-31
• First posted: 2018-01-31
• Last updated: 2025-08-01

Locations

1 site across 1 country: Italy