Trials / Completed
CompletedNCT03416257
TMAO and Atherosclerosis in HIV
Gut Microbial-related Choline Metabolite Trimethylamine-N-oxide is Associated With Progression of Carotid Artery Atherosclerosis in HIV Infection
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 737 (actual)
- Sponsor
- Albert Einstein College of Medicine · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Not accepted
Summary
In the present study, the investigators sought to prospectively examine the associations of plasma levels of TMAO (trimethylamine oxide), choline, betaine, dimethylglycine, and sarcosine with risk of incident carotid artery plaque, assessed by repeated B-mode carotid artery ultrasound imaging over a 7-year period, in women and men with and without HIV infection from the WIHS (Women Interagency HIV Study) and MACS (Multicenter Aids Cohort Study).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | No intervention |
Timeline
- Start date
- 2004-04-12
- Primary completion
- 2013-09-01
- Completion
- 2017-04-04
- First posted
- 2018-01-31
- Last updated
- 2018-06-14
Source: ClinicalTrials.gov record NCT03416257. Inclusion in this directory is not an endorsement.