Clinical Trials Directory

Trials / Completed

CompletedNCT03415750

Everolimus and Tacrolimus Combination for Regression of Left Ventricular Hypertrophy in Renal Transplants

A Single-center,Randomized,Open-label,12 Months Study,2 Parallel Group to Compare the Efficacy of Everolimus Combination + Tacrolimus in Regression of Left Ventricular Hypertrophy vs Tacrolimus + MMF in Renal Transplant Patients

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
20 (actual)
Sponsor
Edoardo Melilli · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Clinical study with two parallel group to compare the efficacy of everolimus combination + tacrolimus in regression of left ventricular hypertrophy vs tacrolimus + mycophenolate mofetil in renal transplant patients in the maintenance phase.

Detailed description

A single-center, randomized, open-label, 12 months study, with two parallel group to compare the efficacy of everolimus combination + tacrolimus in regression of left ventricular hypertrophy vs tacrolimus + mycophenolate mofetil in renal transplant patients in the maintenance phase.

Conditions

Interventions

TypeNameDescription
DRUGEverolimusConversion from Mycophenolate mofetil to Everolimus
DRUGMycophenolate mofetilPatients will remain in Tacrolimus + Mycophenolate mofetil
DRUGTacrolimus

Timeline

Start date
2016-11-01
Primary completion
2020-05-01
Completion
2020-05-01
First posted
2018-01-30
Last updated
2021-01-08

Locations

1 site across 1 country: Spain

Source: ClinicalTrials.gov record NCT03415750. Inclusion in this directory is not an endorsement.