Trials / Completed
CompletedNCT03414164
In Vitro Effects of Procyanidine on Semen Parameter and DFI
In Vitro Effects of Procyanidine on Semen Parameters and DNA Fragmentation Index: a Prospective, Double-blind Trial
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 50 (actual)
- Sponsor
- Aristotle University Of Thessaloniki · Academic / Other
- Sex
- Male
- Age
- 18 Years – 50 Years
- Healthy volunteers
- Not accepted
Summary
Proanthocyanidins are a class of polyphenols found in a variety of plants that have antioxidant activity in vitro, which is stronger than vitamin C or vitamin E. Several studies have been performed evaluating the administration of antioxidant therapy in the form of oral antioxidant supplementation or in vitro addition of antioxidant to culture media during assisted reproductive techniques (ART). However, the impact of in vitro addition of proanthocyanidins to semen has not been studied yet. The research question evaluated in the current study was whether semen samples of infertile men supplemented or not with procyanidine immediately after their production, differ in semen parameters, sperm DFI.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | procyanidine | natural antioxidants |
Timeline
- Start date
- 2017-04-29
- Primary completion
- 2017-11-30
- Completion
- 2017-12-31
- First posted
- 2018-01-29
- Last updated
- 2018-01-29
Locations
1 site across 1 country: Greece
Source: ClinicalTrials.gov record NCT03414164. Inclusion in this directory is not an endorsement.