NCT03413020

Tailored Therapy for Helicobacter Pylori Rescue Treatment

Efficacy of Tailored for Helicobacter Pylori Rescue Treatment Based on Antimicrobial-susceptibility Testing

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 200 (actual)
• Sponsor: Shanghai Jiao Tong University School of Medicine · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

With increasing antibiotic resistance and unsatisfactory results of empiric eradication regimens, tailored therapy may be the best choice to achieve high efficacy for rescue treatment. This study aimed to evaluate the eradication rates, safety, and compliance of antimicrobial susceptibility-based tailored therapy for rescue treatment in patients with Helicobacter pylori infection.

Conditions

• Helicobacter Pylori Infection

Interventions

Type	Name	Description
DRUG	esomeprazole	proton pump inhibitor
DRUG	bismuth Potassium Citrate	gastric mucosal protective drug with anti-H. pylori effect
DRUG	amoxicillin	antibiotic for H. pylori eradication
DRUG	clarithromycin	antibiotic for H. pylori eradication
DRUG	metronidazole	antibiotic for H. pylori eradication
DRUG	levofloxacin	antibiotic for H. pylori eradication

Timeline

• Start date: 2018-01-03
• Primary completion: 2018-07-31
• Completion: 2018-07-31
• First posted: 2018-01-29
• Last updated: 2018-08-07

Locations

1 site across 1 country: China