Clinical Trials Directory

Trials / Suspended

SuspendedNCT03412253

Could Single-anastomosis Gastric Bypass Be a Curative Treatment for Type II Diabetes?

From Diabetes Care to Diabetes Cure; Could Single-anastomosis Gastric Bypass Be a Safe Bridge to Reach This Target in Non-Obese Patients?

Status
Suspended
Phase
N/A
Study type
Interventional
Enrollment
17 (actual)
Sponsor
Ain Shams University · Academic / Other
Sex
All
Age
20 Years – 60 Years
Healthy volunteers
Not accepted

Summary

Single- Anastomosis gastric bypass (SAGB) is a potentially curative line of treatment for type II diabetes mellitus (T2DM) patients with BMI 25-30 kg/m2. Accordingly, SAGB could be integrated into T2DM treatment algorithm

Detailed description

Background: T2DM has been considered as a chronic progressive incurable metabolic disease. Single-anastomosis gastric bypass (SAGB) was shown to be effective in obese patients in terms of weight reduction and T2DM remission, yet its effect on non-obese diabetics is not extensively studied. In this study, we tried to determine the anthropometric and glycemic outcomes of SAGB as a proposed line of treatment for type II diabetes mellitus (T2DM) patients with body mass index (BMI) 25-30 kg/m2. Methods: From November 2013 to March 2016, a prospective study has been conducted at Ain-Shams University hospitals on 17 consecutive patients undergone SAGB. The demographic and anthropometric data of the patients, as well as their relevant laboratory results, were reported, other data including anti-diabetic medications, co-morbid metabolic diseases were also assessed. All patients were scheduled for laparoscopic SAGB and were advised to come in regular follow up at 1, 3, 6, 12 and 18 months postoperatively. T2DM Remission is considered if glycosylated hemoglobin (HbA1c) \<6.5 % and fasting plasma glucose (FPG) \< 126 mg/dl for at least 1 year without medication.

Conditions

Interventions

TypeNameDescription
PROCEDURESingle-Anastomosis Gastric Bypass surgery (SAGB).We checked the effect of SAGB on patients suffered from T2DM with BMI 25-30

Timeline

Start date
2013-11-01
Primary completion
2016-03-31
Completion
2018-02-04
First posted
2018-01-26
Last updated
2018-01-26

Source: ClinicalTrials.gov record NCT03412253. Inclusion in this directory is not an endorsement.