Trials / Completed
CompletedNCT03411642
Comparative Effectiveness Study of Transthoracic and Transesophageal Echocardiography in Stroke
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 494 (actual)
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The Comparative Effectiveness Study of Transthoracic and Transesophageal Echocardiography in Stroke (CONTEST) aims at assessing the diagnostic value of transesophageal echocardiography (TEE) and transthoracic echocardiography (TTE) with regards to treatment consequences in patients with acute ischemic stroke.
Detailed description
For this purpose, the investigators will perform a prospective multicenter diagnostic comparative effectiveness study. Patients with acute stroke will be studied by both TTE and TEE. Patients with already defined stroke etiology and determined secondary prevention will be excluded from the trial. Treatment relevant diagnostic findings will be identified by a central endpoint adjudication committee. In order to demonstrate a hypothesized 2% absolute increase in the number of treatment relevant diagnostic findings by TEE as compared to TTE, 880 stroke patients will be enrolled in six German stroke centers. CONTEST will allow answering the question whether and for which group of stroke patients TEE is indicated in addition to TTE. By this, the study will provide evidence to guide justified recommendations for echocardiography in acute stroke patients.
Conditions
Timeline
- Start date
- 2017-07-01
- Primary completion
- 2019-06-30
- Completion
- 2019-08-31
- First posted
- 2018-01-26
- Last updated
- 2023-09-13
- Results posted
- 2023-09-13
Locations
4 sites across 1 country: Germany
Source: ClinicalTrials.gov record NCT03411642. Inclusion in this directory is not an endorsement.