NCT03408522

Troponin Elevation After Major Noncardiac Surgery 2

Clinical Characteristics and Functional Outcomes of Postoperative Myocardial Injury: A Prospective Cohort Study - Troponin Elevation After Major Noncardiac Surgery 2

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 1,000 (estimated)
• Sponsor: UMC Utrecht · Academic / Other
• Sex: All
• Age: 60 Years
• Healthy volunteers: Not accepted

Summary

Major adverse cardiac events (MACE) are a leading cause of mortality in patients undergoing noncardiac surgery. Patients with perioperative myocardial injury (PMI), defined as either myocardial infarction and lower elevations in cardiac troponin, are also at substantially increased risk of additional cardiac and noncardiac complications. Accordingly, it is plausible to assume that PMI negatively affects quality of life in terms of disability. The aim of this study is to investigate and compare the independent prognostic effects of the different PMI phenotypes (myocardial infarction and non-infarct troponin elevations) and noncardiac complications on disability in patients undergoing elective noncardiac surgery.

Conditions

• Perioperative Myocardial Infarction
• Disability
• Perioperative/Postoperative Complications

Timeline

• Start date: 2018-01-29
• Primary completion: 2019-06-30
• Completion: 2019-12-31
• First posted: 2018-01-24
• Last updated: 2019-01-16

Locations

3 sites across 2 countries: Canada, Netherlands