NCT03408418

L-PRF in Alveolar Ridge Preservation

Tomographic and Histological Evaluation of Postextraction Sockets Treated With Leucocyte- and Platelet-rich Fibrin: a Randomized Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 48 (actual)
• Sponsor: Rio de Janeiro State University · Academic / Other
• Sex: All
• Age: 17 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The effect of leucocyte- and platelet-rich fibrin (L-PRF) for enhancing the healing after dental extractions is still a matter of debate. The available literature suggests that L-PRF performs positive effect to improve alveolar preservation resulting in less bone resorption on extraction sockets. L-PRF is a second generation of platelet concentrate produced without biochemical blood manipulation. L-PRF is composed by three key parameters: first, the presence of platelets; second, the presence of leucocytes; third, the density and complex organization of the fibrin matrix architecture produced by a natural polymerization process. The theory is that this key parameters acts to produce a faster bone healing.

Conditions

• Bone Loss, Alveolar

Interventions

Type	Name	Description
PROCEDURE	Platelet-rich fibrin	The use of autologous platelet-rich fibrin after tooth extraction to promote bone healing and alveolar ridge preservation

Timeline

• Start date: 2018-03-01
• Primary completion: 2019-03-01
• Completion: 2019-03-01
• First posted: 2018-01-24
• Last updated: 2019-03-26

Locations

1 site across 1 country: Brazil