Trials / Terminated
TerminatedNCT03404310
Zinc Sulfate for Human Papillomavirus (HPV)
Oral Zinc Sulfate for the Treatment of High Risk Cervical HPV Versus Placebo
- Status
- Terminated
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 21 (actual)
- Sponsor
- Corewell Health West · Academic / Other
- Sex
- Female
- Age
- 21 Years – 65 Years
- Healthy volunteers
- Not accepted
Summary
The Human Papillomavirus (HPV) is well established as the primary causative agent in both warts and cervical cancer. Although cervical high risk HPV (hrHPV) infections have a high rate of spontaneous resolution this takes time and the infection can cause cervical cells to progress to precancerous and cancerous lesions. Zinc has been shown to play a central role in immunity. This study is to determine if oral zinc sulfate can improve clearance rates of high risk HPV versus placebo.
Detailed description
Upon enrollment eligible participants will be randomized and given a three-month supply of zinc sulfate or placebo to be taken as directed. They will have zinc serum lab testing at enrollment and upon study completion. Patients will also be asked to complete short questionnaires and to make study staff aware of any side effects they should experience.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Zinc Sulfate | Participant will take one 220mg tablet twice daily for three months. |
| OTHER | Placebo (Gelatin Tablet) | Participant will take one tablet twice daily for three months. |
Timeline
- Start date
- 2017-10-24
- Primary completion
- 2019-06-28
- Completion
- 2019-06-28
- First posted
- 2018-01-19
- Last updated
- 2023-09-22
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT03404310. Inclusion in this directory is not an endorsement.