NCT03404011

Acute Effects of Propylene Glycol/Glycerol Intake on Blood Parameters

Acute Effects of Propylene Glycol/Glycerol Intake on Cardiorespiratory Blood Parameters

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (actual)
• Sponsor: Université Libre de Bruxelles · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to evaluate the acute effect of propylene glycol and glycerol intake on cardiorespiratory blood parameters.

Detailed description

Background : Propylene glycol/glycerol intake is increasingly popular. Acute effect of propylene glycol and glycerol intake on cardiorespiratory blood parameters is unknown. The investigators postulate that intake of propylene glycol and glycerol could modifiy cardiorespiratory blood parameters. Aims of this study : to test the following hypotheses : 1\) Acute intake of propylene glycol and glycerol modifies cardiorespiratory blood parameters. To test this hypothesis, we will perform blood samples before and after intake of propylene glycol and glycerol. Participants will be tobacco smoker between 18 and 70 years old, with multiple cardiovascular risk factors, and who will undergo a cardiac catherization. After the cardiac catherization, the catheter will be used to perform serial blood samples.

Conditions

• Metabolic Complication

Interventions

Type	Name	Description
OTHER	Propylene glycol and Glycerol intake	Intake of 1 gram of propylene glycol/Glycerol mix (50:50). Blood sample before, 5 minutes and 20 minutes after intake.
DEVICE	Mimicking intake	Mimicking propylene glycol/glycerol intake with the device turns off. Blood sample before, 5 minutes and 20 minutes after intake.

Timeline

• Start date: 2018-01-15
• Primary completion: 2018-12-30
• Completion: 2018-12-30
• First posted: 2018-01-19
• Last updated: 2019-04-17

Locations

1 site across 1 country: Belgium