Clinical Trials Directory

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UnknownNCT03402711

Registry of Bleeding Risk in Real World Chinese Acute Coronary Syndrome Patients-II

Status
Unknown
Phase
Study type
Observational
Enrollment
5,500 (estimated)
Sponsor
Chinese PLA General Hospital · Academic / Other
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

The present study was designed to observe the incidence of bleeding events and characteristics of bleeding and exploratively analyse bleeding related biomarkers and gene polymorphisms in ACS patients undergoing PCI.

Detailed description

Acute coronary syndrome (ACS) is a group of clinical syndromes characterized by rupture or erosion of coronary atherosclerotic plaques secondary to complete or incomplete thrombus formation. With the development of antithrombotic drugs and percutaneous coronary interventional therapy, bleeding has become one of the major complications for ACS patients after PCI.Moreover,Bleeding after PCI therapy significantly increased short-term and long-term risk of death. However, there is a lack of data on the risk of bleeding in ACS patients treated with PCI in the clinical reality world of china. Therefore,the present study was designed to observe the incidence of bleeding events and characteristics of bleeding and exploratively analyse bleeding related biomarkers and gene polymorphisms in ACS patients undergoing PCI. The present study was designed to observe the incidence of bleeding events and characteristics of bleeding and exploratively analyse bleeding related biomarkers and gene polymorphisms in ACS patients undergoing PCI. This study will provide sufficient and reliable evidence for the risk of bleeding and the choice of antithrombotic drugs in ACS patients undergoing PCI in China, and provide a reference for individual antithrombotic therapy after PCI.

Conditions

Timeline

Start date
2017-12-14
Primary completion
2020-04-01
Completion
2021-04-01
First posted
2018-01-18
Last updated
2018-01-18

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT03402711. Inclusion in this directory is not an endorsement.