NCT03402373

Evaluation of the Nutritional Supplement Lycoderm on Its Impact on Skin Parameters

A 16-Week Double-Blind, Randomized, Placebo-Controlled Study Evaluating the Nutritional Supplement Lycoderm on Its Impact on Skin Parameters in Healthy Female Subjects

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: LycoRed Ltd. · Industry
• Sex: Female
• Age: 35 Years – 55 Years
• Healthy volunteers: Accepted

Summary

Carotenoids and polyphenols are assumed to have an active role in skin health. Sources for these phytonutrient are fruits and vegetables. They are widely applied as skin protectants, and supplementation with carotenoids have shown to protect against erythema caused by UV-radiation. UV radiation generates reactive oxygen species in the skin, which induces cellular signaling that may impair cell cycle, cell growth, and regeneration or repair processes.

Detailed description

The face holds an integral role in human social communication and how humans are perceived as attractive. In addition to structural facial features, studies have shown that skin appearance is highly weighed in the perception of beauty and is determined primarily by its coloration and surface topography. Aging is caused by two processes, intrinsic and extrinsic. The sun is the primary cause of extrinsic aging and has also been shown to alter the normal course of intrinsic or natural aging. On the molecular level, various hypotheses have been proposed to explain aging, with free radical theory being prominent. The free radical theory addresses the concept of intrinsic biological instability of living systems, in which free radicals and other reactive oxygen species (ROS) damage biomolecules, and this damage results in aging of the skin (as well as other systems). The aim of this study is to examine the effects of an oral antioxidant supplement on skin aging and skin condition.

Conditions

• Skin Care

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Lycoderm	soft gel contains nutritional supplement
DIETARY_SUPPLEMENT	Placebo	soft gel without active ingredients

Timeline

• Start date: 2017-11-17
• Primary completion: 2019-03-17
• Completion: 2019-05-30
• First posted: 2018-01-18
• Last updated: 2019-07-02

Locations

1 site across 1 country: United States