NCT03396341

Responses to Genetic Risk Modifier Testing Among Women With BRCA1/2 Mutations

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 400 (estimated)
• Sponsor: Memorial Sloan Kettering Cancer Center · Academic / Other
• Sex: Female
• Age: 25 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to describe how women with BRCA1/2 mutations react to genetic risk modifier testing, and to examine how they make decisions about their healthcare.

Conditions

• Genetic Testing
• BRCA1/2

Interventions

Type	Name	Description
OTHER	Salvia sample	salvia sample
BEHAVIORAL	Questionnaires	Participants will complete Assessment #1 questionnaires. Participants will be contacted 1 week later (+/- 1 week) to complete Assessment #2 questionnaires. Participants will be contacted 6 months (+/- 3 weeks) following the receipt of their genetic risk modifier results to complete Assessment #3 questionnaires. Participants will be encouraged to complete Assessments #2 and #3 via email using the secure, approved REDCap system

Timeline

• Start date: 2018-01-04
• Primary completion: 2027-01-01
• Completion: 2027-01-01
• First posted: 2018-01-10
• Last updated: 2026-02-09

Locations

7 sites across 1 country: United States