NCT03395093

BIS of Sedation Depth During Flexible Bronchoscopy.

Bispectral Index Monitoring of Sedation Depth During Flexible Bronchoscopy: With or Without Fentanyl .

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 500 (actual)
• Sponsor: Nanjing First Hospital, Nanjing Medical University · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Fentanyl is analgesia medication. There has not pain nerve in the lung. Flexible bronchoscopy(FB) is used in the respiratory medicine. So people will not feel pain in the process of FB. The purpose of the study is to know if Fentanyl is useful in the conscious sedation of FB.

Detailed description

Fentanyl is opioid receptor agonists. It is a fast-acting, short duration and potent analgesics. Flexible bronchoscopy (FB) is mostly used in the diagnosis and therapy in the respiratory disease. As we know, there has not pain nerve in the lung. People will not feel pain when they are in FB. If fentanyl will be effective in FB? Our study will observe the effect of conscious sedation in FB with fentanyl or without fentanyl.

Conditions

• Pulmonary Disease

Interventions

Type	Name	Description
DRUG	Fentanyl	Five minutes before the patients is done the flexible bronchoscopy, fentanyl will be intravenous injected.
DRUG	Midazolam	Five minutes before the patients is done the flexible bronchoscopy, midazolam will be intravenous injected.
DRUG	Propofol	Propofol will be intravenous injected as soon as the flexible bronchoscopy begins.
DEVICE	Bispectral Index monitoring	Bispectral Index monitoring will be used in the process of the flexible bronchoscopy.

Timeline

• Start date: 2016-07-21
• Primary completion: 2018-06-30
• Completion: 2018-12-31
• First posted: 2018-01-10
• Last updated: 2018-01-10