Clinical Trials Directory

Trials / Withdrawn

WithdrawnNCT03394976

Prospective Evaluation of an RDT to Screen for Gambiense HAT and Diagnose P. Falciparum Malaria

Prospective Evaluation of a Rapid Diagnostic Test to Screen for Gambiense Human African Trypanosomiasis and Diagnose Plasmodium Falciparum Malaria

Status
Withdrawn
Phase
Study type
Observational
Enrollment
0 (actual)
Sponsor
Foundation for Innovative New Diagnostics, Switzerland · Academic / Other
Sex
All
Age
6 Years
Healthy volunteers
Accepted

Summary

A prototype rapid diagnostic test (RDT) to simultaneously screen for gambiense human African trypanosomiasis (HAT) and diagnose P. falciparum malaria (the "HAT/malaria combo") has recently been developed. The performance of this prototype has been evaluated in a retrospective study that showed that its diagnostic performance for HAT and malaria was equivalent to the performance of the SD BIOLINE HAT 2.0 and the SD BIOLINE Malaria Ag P.f tests, respectively. The purpose of this study is to prospectively evaluate the performance of the test in settings where P. falciparum malaria is endemic, and which are either endemic or non-endemic for HAT. This will enable the assessment of the suitability of the HAT/malaria combo RDT as a diagnostic test for malaria, and a screening test for HAT in pre-elimination and post-elimination contexts, respectively.

Conditions

Interventions

TypeNameDescription
DIAGNOSTIC_TESTNo interventionNo intervention

Timeline

Start date
2022-01-31
Primary completion
2022-12-31
Completion
2022-12-31
First posted
2018-01-09
Last updated
2024-01-09

Source: ClinicalTrials.gov record NCT03394976. Inclusion in this directory is not an endorsement.