NCT03394833

Hemodynamic Stability During Induction of Anaesthesia

Hemodynamic Stability During an Induction of Anaesthesia: A Randomized, Non-blinded Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: Umeå University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The study aim is to investigate if preoperative volume bolus based on lean body weight could preserve mean arterial pressure during target controlled infusion of anaesthesia (TCI) or rapid sequence induction of anaesthesia (RSI) in non-cardiac, non-morbidly obese surgery.

Detailed description

40 individuals are enrolled to TCI and RSI groups respectively. The randomization process for preoperative fluid bolus prior to induction of anaesthesia is conducted in respective group at the day of surgery. Preoperative colloid fluid therapy (6 ml/kg LBW, Gelofusine™, Fresenius Kabi Ab, Sweden) is infused rapidly before non-invasive baseline blood pressure (NIBP) measurements in twenty individuals in each group. No other intravenous fluids before induction of anaesthesia. NIBPs, pulse frequency, peripheral saturation (SpO2) are registered and collected 20 minutes post induction.

Conditions

• Hemodynamic Instability
• Fluid Therapy
• Anesthesia; Adverse Effect

Interventions

Type	Name	Description
OTHER	gelofusine	Preoperative colloid fluid bolus 6ml/kg ideal body weight

Timeline

• Start date: 2017-11-20
• Primary completion: 2018-12-15
• Completion: 2019-04-30
• First posted: 2018-01-09
• Last updated: 2019-09-26

Locations

1 site across 1 country: Sweden