Trials / Completed
CompletedNCT03391622
Thrombin Generation Values and Percutaneous Coronary Intervention Results.
The Correlation Between Thrombin Generation Values and Percutaneous Coronary Intervention Results in Active Ischemic Heart Disease Patients.
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 128 (actual)
- Sponsor
- HaEmek Medical Center, Israel · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Cardiovascular diseases are the most common cause of death in the western world. Myocardial infarction pathogenesis usually involves the development of an atherosclerotic plaque and thrombus. Past research has shown a correlation between thrombin generation values and ischemic heart disease, however, to our knowledge no investigation has been done into the correlation of thrombin generation and cardiac catheterization results in ischemic heart disease patients. In the current research the investigator will investigate the correlation of thrombin generation values using calibrated automated thrombogram and cardiac catheterization results in active ischemic heart disease patients.
Detailed description
The aim of our study is to investigate the correlation of thrombin generation values using calibrated automated thrombogram and cardiac catheterization results in active ischemic heart disease patients. In total 340 patients are planned for inclusion in this trial. After signing an informed consent a blood sample will be obtained from each participant. the investigators will measure the thrombin generation over time in plasma assessed by the calibrated automated thrombogram (CAT). In addition information about the course and results of cardiac catheterization will be collected.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | Calibrated Automated Thrombogram | blood samples will be collected . Thrombin generation in platelet-poor plasma will be measured by means of the Calibrated Automated Thrombogram (CAT). |
Timeline
- Start date
- 2018-04-01
- Primary completion
- 2020-08-30
- Completion
- 2020-08-30
- First posted
- 2018-01-05
- Last updated
- 2022-11-08
Locations
1 site across 1 country: Israel
Source: ClinicalTrials.gov record NCT03391622. Inclusion in this directory is not an endorsement.