NCT03390361

Release of Proinflammatory Cytokines (IL-1β, IL-6) and Total-prostaglandin (PG) Following Femtosecond Laser-assisted Cataract Surgery Compared to Manual Cataract Surgery

Intraindividual Comparison of Proinflammatory Cytokines (IL-1β, IL-6) and Total-prostaglandin (PG) Following Femtosecond Laser-assisted Cataract Surgery Using a Low-energy, High-frequency Femtosecond Laser-Device Compared to Manual Cataract Surgery

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Medical University of Vienna · Academic / Other
• Sex: All
• Age: 40 Years
• Healthy volunteers: Accepted

Summary

Patients with bilateral age related cataract will be included in the study. Manual cataract surgery (MCS) will be performed in one eye and laser cataract surgery (LCS) in the corresponding eye. LCS will be performed with an approved femtosecond laser (FSL) device with an integrated imaging system. After surgery aqueous humour will be collected and screened with Enzyme-linked Immunosorbent Assay (ELISA) Kits for Interleukin-1β; Interleukin-6 and PG.

Conditions

• Age Related Cataracts

Interventions

Type	Name	Description
DEVICE	Femtosecond Laser-assisted	Laser cataract surgery will be performed in one eye
PROCEDURE	Manual Cataract Surgery	Manual cataract surgery will be performed in contralateral eye

Timeline

• Start date: 2016-04-05
• Primary completion: 2016-08-09
• Completion: 2016-11-25
• First posted: 2018-01-04
• Last updated: 2018-01-05

Locations

1 site across 1 country: Austria