NCT03390010

Misoprostol Versus Active Management of Labour in CS

Intrauterine Misoprostol With Active Management of Labour Versus Active Management of Labour for Prevebtion of Postpartum Hemorage in Cesarean Section ,Randomized Controlled Trial

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 300 (actual)
• Sponsor: Aljazeera Hospital · Academic / Other
• Sex: Female
• Age: 18 Years – 42 Years
• Healthy volunteers: Accepted

Summary

Several treatment strategies are emplemented to prevent post delivery hemorage and decreasing maternal morbidity and mortality .

Detailed description

Many approved drugs are used in prophylaxis against postpartum hemorage from these medications are the (syntocinon combined with methergine ) that are known as active management of labour drugs . Moreover there is misotac , that also guards against postpartum hemorage . All these medications act in a different way to cause uterine contraction post delivery to prevent uterine atony . -Here we are comparing the additive value of misotac intrauterine to syntocinon and methergine in comparison to the usually used syntocinon plus methergine .

Conditions

• Cesarean Section

Interventions

Type	Name	Description
DRUG	Misoprostol + syntocinon and using extra uterotonic drugs when needed ; methergine	medical prophylaxis against postpartum atony and postpartum hemorage by giving misoprostol plus syntocinon and using extra uterotonic drugs when needed ; methergine, carboprost
DRUG	Syntocinon and using extra uterotonic drugs when needed ; methergine carboprost	medical prophylaxis against postpartum atony and postpartum hemorage by giving syntocinon and using extra uterotonic drugs when needed ; methergine, carboprost

Timeline

• Start date: 2017-12-28
• Primary completion: 2018-02-28
• Completion: 2018-03-06
• First posted: 2018-01-04
• Last updated: 2022-11-16

Locations

1 site across 1 country: Egypt