NCT03389711

INCMNSZ - Rheumatoid Arthritis Cohort

INCMNSZ Early Rheumatoid Arthritis Cohort

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 237 (estimated)
• Sponsor: National Institute of Medical Sciences and Nutrition, Salvador Zubiran · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Identify Rheumatoid Arthritis patients diagnose within first 12 months since the beginning of the disease related symptoms. Initiate proper treatment according to international standards in order to achieve remission/low disease activity status.

Detailed description

* Provide an standardized follow up by a multidisciplinary specialized team. * Create a biological (blood) bank to develop future research projects. * Create a database with the clinical, serologic, radiographic and functional status patients data. * Define comorbidities and mortality causes. * Begin an educational program to improve patient disease self-knowledge

Conditions

• Early Rheumatoid Arthritis
• Rheumatoid Arthritis

Interventions

Type	Name	Description
COMBINATION_PRODUCT	DMARD´s and multidisciplinary treatment	At study enrollment, medical history, disease-specific autoantibodies, ACR 1987 classification criteria for RA were applied. Medical evaluations were standardized and included at least 66 swollen and 68 tender joint counts, acute reactant-phase determinations , patient and physician reported outcomes, comorbidity established by record review, and treatment assessments (name, dose and schedule of all drug they were taking) along with an evaluation of persistence, at six-month intervals. Patients were evaluated by a single rheumatologist every two months during the first two years of follow-up, and every two, four or six months thereafter. Also the following scores: Michigan Hand Outcome Questionnaire (MHQ), Disabilities of the Arm, Shoulder and Hand Outcome Measure (DASH),Mayor Depressive Episodes (MDE) was defined using the Mini International Neuropsychiatric Interview and the severity of depressive symptoms was assessed with the Beck Depression Inventory (BDI-II).

Timeline

• Start date: 2004-02-04
• Primary completion: 2024-02-04
• Completion: 2024-02-04
• First posted: 2018-01-04
• Last updated: 2022-04-06

Locations

1 site across 1 country: Mexico