Trials / Unknown
UnknownNCT03389191
A Clinical Trial of Acyclovir for Viral Uveitis
A Clinical Trial of Oral Acyclovir in Viral Uveitis
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- Sponsor
- Xiaomin Zhang · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
This project is designed to test the hypothesis that acyclovir is clinically useful for patients with refractory viral uveitis.
Detailed description
Approval of the study was obtained from the hospital's ethical committee. The study design and methodology followed the tenets of Declaration of Helsinki. All patients were provided with written informed consent and received a thorough explanation of the study design, aims, benefits and potential risks. This is a prospective non-comparative interventional study. Aqueous humor samples were collected from participants to virus detection. Participants will take oral acyclovir 100 mg three times a day and data will be collected prospectively with regard to ophthalmologic outcomes. Study participants will be followed for up to 12 months to determine efficacy, and an additional 30 days for safety reports. Descriptive statistics will be gathered on participant demographics, uveitis characteristics, change in immunosuppressive medications, number of responders, ophthalmologic measures and change in corticosteroid dose during the study period.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Acyclovir |
Timeline
- Start date
- 2017-01-01
- Primary completion
- 2019-12-01
- Completion
- 2021-12-01
- First posted
- 2018-01-03
- Last updated
- 2021-04-05
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT03389191. Inclusion in this directory is not an endorsement.