NCT03388411

Nutritional Intake and Gut Microbiome

Nutritional Intake, Metabolic Abnormalities and Gut Microbiome in Children

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 61 (actual)
• Sponsor: Hallym University Kangnam Sacred Heart Hospital · Academic / Other
• Sex: All
• Age: 12 Years
• Healthy volunteers: Accepted

Summary

Pediatric obesity has been increasing in prevalence, but concerns have been raised around the world because no treatment has been found. Recently, however, research on gut microbiome has begun to become a new alternative. It has been shown that changes in the microbiome in adults may induce obesity. However, the results on children are still scarce. Unlike adults, children have few external factors such as alcohol, tobacco, stress, and cancer, making them suitable for obesity-related gut microbiome studies. The investigators will use Illumina MiSeq platform for 16s rRNA metagenomics profiling in children. In this study, the investigators aimed to analyze the relationship between pediatric obesity, gut microbiome profile, blood biomarkers relevant to metabolic syndrome, and nutrient intake data.

Conditions

• Obesity, Childhood

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Gut microbiome profiling	Gut microbial profiling will be done with next-generation sequencing targeting bacterial 16s rRNA genes.

Timeline

• Start date: 2017-10-18
• Primary completion: 2018-10-12
• Completion: 2018-10-12
• First posted: 2018-01-03
• Last updated: 2019-02-27

Locations

1 site across 1 country: South Korea