NCT03388086

Efficacy of Two Onabotulinum Toxin Doses

Comparing the Efficacy of Two Doses of Onabotulinum Toxin for the Treatment of Neurogenic Detrusor Overactivity - a Retrospective Cohort Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 56 (actual)
• Sponsor: Swiss Paraplegic Research, Nottwil · Network
• Sex: All
• Age: 18 Years – 99 Years
• Healthy volunteers: Not accepted

Summary

The changes in bladder function after the injection of Onabotulinum toxin into the detrusor in individuals with neurogenic bladder overactivity will be investigated retrospectively. The records of all patients treated with Onabotulinum toxin injections into the detrusor since 2000 will be evaluated. The changes in the urodynamic values after the injection of 300 units of Onabotulinum toxin will be compared with the changes after the injection of 200 units. Furthermore, the differences in urinary continence, duration between injections, side effects and complications between the two groups will be investigated.

Conditions

• Neurogenic Bladder
• Overactive Detrusor

Interventions

Type	Name	Description
DRUG	Injection of Onabotulinum toxin	multiple injections of Onabotulinum toxin into the detrusor muscle

Timeline

• Start date: 2018-02-01
• Primary completion: 2019-04-30
• Completion: 2019-07-31
• First posted: 2018-01-02
• Last updated: 2019-08-06

Locations

1 site across 1 country: Switzerland