NCT03387956

Intrathecal Atropine to Prevent Postoperative Nausea and Vomiting

Intravenous Dexamethasone Combined With Intrathecal Atropine to Prevent Morphine-related Nausea and Vomiting After Cesarean Delivery: A Randomized Double-blinded Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 120 (actual)
• Sponsor: Assiut University · Academic / Other
• Sex: Female
• Age: 20 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

optimal postoperative pain control with intrathecal morphine, with proper prevention of postoperative nausea and vomiting. Dexamethasone, and or atropine could offer some protection against nausea and vomiting.

Detailed description

One of the gold standards for analgesia following cesarean delivery is intrathecal morphine, which is not devoid of complications namely postoperative nausea and vomiting. We evaluated the antiemetic effect of intravenous dexamethasone combined with intrathecal atropine after cesarean delivery under spinal bupivacaine plus morphine anesthesia.

Conditions

• Postoperative Nausea

Interventions

Type	Name	Description
DRUG	Intrathecal atropine	100ug intrathecal atropine will be injected with spinal anesthesia
DRUG	dexamethasone	intravenous 8 mg dexamethasone (2ml).

Timeline

• Start date: 2017-03-20
• Primary completion: 2017-07-28
• Completion: 2017-08-10
• First posted: 2018-01-02
• Last updated: 2018-06-06

Locations

1 site across 1 country: Egypt