NCT03387345

Barley and Rice Mixture Effects on Blood Glucose

β-glucan Rich Barley and Rice Mixes and Post-prandial Glycemia - a Dose Response Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 39 (actual)
• Sponsor: Arizona State University · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The purpose of this research was to investigate 5 different formulations of whole grain barley and refined white rice against a control of white bread on post-prandial glycemic response, as well as self-reported hunger/satiety in a randomized cross-over trial.

Detailed description

Beta-glucan-rich barley has been shown to improve glycemic response, reduce hunger and increase satiety. Nutrient-dense grain mixtures that include a new cultivar of barley (Sustagrain, Ardent Mills, LLC) with exceptionally high dietary fiber content may help individuals meet their dietary fiber needs while minimizing the rapid increase in blood glucose following the consumption of a refined grain product. The primary objective of this study was to compare the effects of five different test meals containing varying amounts of whole-grain barley and refined white rice to white bread on post-prandial blood glucose concentrations. A secondary aim was to evaluate changes in self-reported hunger and satiety following the consumption of each treatment. This study was a single-site, blinded, randomized crossover trial among 24 healthy adults. Each participant consumed the following treatments: 100% Sustagrain barley flakes, 100% Sustagrain steel cut barley , an 80/20 rice-steel cut Sustagrain barley mix, a 50/50 rice-steel cut Sustagrain barley mix, 100% rice, and white bread.

Conditions

• Blood Glucose
• Dietary Fiber
• Hunger

Interventions

Type	Name	Description
OTHER	100% steel cut barley	25 g of available carbohydrate was delivered to participants via steel cut Sustagrain barley (Ardent Mills, LLC).
OTHER	100% barley flakes	25 g of available carbohydrate was delivered to participants via Sustagrain barley flakes (Ardent Mills, LLC).
OTHER	50/50 rice-barley mix	25 g of available carbohydrate was delivered to participants via a 50/50 mixture (by weight) of Goya medium grain white rice and steel cut Sustagrain barley (Ardent Mills, LLC).
OTHER	80/20 rice-barley mix	25 g of available carbohydrate was delivered to participants via a 80/20 mixture (by weight) of Goya medium grain white rice and steel cut Sustagrain barley (Ardent Mills, LLC).
OTHER	100% rice	25 g of available carbohydrate was delivered to participants via Goya medium grain white rice
OTHER	white bread	25 g of available carbohydrate was delivered to participants via Sara Lee Classic White Bread (Bimbo Bakeries USA, Inc.)

Timeline

• Start date: 2017-02-13
• Primary completion: 2017-09-04
• Completion: 2017-09-18
• First posted: 2018-01-02
• Last updated: 2018-01-02

Locations

1 site across 1 country: United States