NCT03386318

Oxycodone Concentration in the Blood After Oral Premedication

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 20 (actual)
• Sponsor: Sahlgrenska University Hospital · Academic / Other
• Sex: Female
• Age: 30 Years – 60 Years
• Healthy volunteers: —

Summary

Oxycodone is an opioid frequently given orally as a premedication prior to any kind of surgery. The initial studies are performed on healthy testpersons and is not given in surgery. The investigators want to explore serum concentration over time (5h) and relate this to Visual Analoge Scale (VAS) postoperatively but also to given mg/kg

Detailed description

Oxycodone is an opioid frequently given orally as a premedication prior to any kind of surgery. The initial studies are performed on healthy test-persons and is not given in surgery. The investigators want to explore serum concentration over time (5h) and relate this to Visual Analoge Scale (VAS) postoperatively but also to given mg/kg 20 female patients between 30 and 60 years will be included after informed consent. They will have day-surgery. The patients will receive 5 mg oxycodone if weighing less than 60 kg and 10 mg if weighing over 60 kg. Serum samples will be taken 1, 2,3,4, and 5 hours after medication intake and serum concentrations will be analyzed

Conditions

• Oxycontin

Interventions

Type	Name	Description
DRUG	Oxycodone	Serum concentration per hour from 1 to 5 h

Timeline

• Start date: 2019-01-01
• Primary completion: 2020-05-10
• Completion: 2021-05-01
• First posted: 2017-12-29
• Last updated: 2022-05-10

Locations

1 site across 1 country: Sweden

Regulatory

• FDA-regulated drug study