NCT03383315

Role of Prophylactic Metoclopramide With Tramadol in Trauma Patients

Role of Prophylactic Metoclopramide With Tramadol in Trauma Patients: A Randomised, Double Blind Placebo Controlled Trial

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 191 (actual)
• Sponsor: University of Malaya · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Tramadol is widely used as analgesic in trauma patients. However, it causes side effects, most notably nausea and vomiting. This study aim to determine the role of prophylactic metoclopramide in preventing tramadol induced nausea and vomiting.

Conditions

• Trauma
• Opioid Analgesic Adverse Reaction

Interventions

Type	Name	Description
DRUG	Tramadol	One dose of intravenous tramadol 50mg
DRUG	Metoclopramide	One dose of intravenous metoclopramide 10mg
DRUG	Placebo	Sodium chloride 0.9%

Timeline

• Start date: 2017-07-01
• Primary completion: 2017-09-30
• Completion: 2017-09-30
• First posted: 2017-12-26
• Last updated: 2017-12-26

Locations

1 site across 1 country: Malaysia