NCT03380611

Algae and Cholesterol Absorption

Effects of Wakame and Spirulina Consumption on Intestinal Cholesterol Absorption in Non- Hypercholesterolemic Men and Women

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 36 (actual)
• Sponsor: Maastricht University Medical Center · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The primary objective of this study is to investigate the effects of wakame and spirulina consumption on intestinal cholesterol absorption.

Detailed description

Objectives: Secondary objectives are to investigate the effects of wakame and spirulina consumption on fasting markers for lipid metabolism, glucose metabolism and blood pressure. Study design: This study is a double-blinded, randomized, placebo-controlled, crossover intervention trial consisting of three intervention periods of 17 days each, separated by a minimum washout period of 14 days. Study population: The study population will consist of 37 healthy, non-hypercholesterolemic men and women aged between 18 and 70 years. Intervention: All subjects will receive wakame, spirulina and placebo capsules in randomized order. Subjects will be asked to consume 12 capsules per day for 17 days, which is equal to 4.8 grams of wakame or spirulina a day.

Conditions

• Intestinal Cholesterol Absorption

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Wakame	Consumption of 4.8 grams wakame per day for 17 days
DIETARY_SUPPLEMENT	Spirulina	Consumption of 4.8 grams spirulina per day for 17 days
DIETARY_SUPPLEMENT	Control	Consumption of microcrystalline cellulose for 17 days

Timeline

• Start date: 2017-10-24
• Primary completion: 2018-08-16
• Completion: 2018-08-16
• First posted: 2017-12-21
• Last updated: 2018-10-19

Locations

1 site across 1 country: Netherlands