NCT03378557

Periprosthetic Fracture Registry (PPFx)

Multicenter Prospective Registry for Periprosthetic Fractures After Hip or Knee Arthroplasty

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 600 (estimated)
• Sponsor: AO Innovation Translation Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This registry supports international data collection and research on PPFx treatments after hip and knee arthroplasty. A registry such as this ultimately aims to provide far-reaching benefits to society including reduced morbidity and mortality, improved patient safety, improved quality of care and medical decision-making, reduced medical spending, and advances in orthopaedic science.

Detailed description

To close the gap of missing clinical evidence regarding the treatment of periprosthetic fractures after arthroplasty of the hip or the knee with osteosynthesis. To drive further study hypotheses and to answer unforeseen questions. Main questions to be answered by the registry include (but are not exclusive) the following: 1. Influence of implants on outcome 2. Influence of surgical techniques on outcome 3. Influence of bone grafting on outcome 4. Identification of risk factors for failure 5. Identification of postoperative rehabilitation programs and its possible influence on the outcome 6. Influence of fracture type on outcome 7. To serve as a comparative dataset for future studies with improved implants and techniques

Conditions

• Periprosthetic Fractures
• Periprosthetic Fracture Around Prosthetic Joint Implant

Timeline

• Start date: 2018-12-31
• Primary completion: 2027-01-31
• Completion: 2027-03-31
• First posted: 2017-12-20
• Last updated: 2025-09-12

Locations

13 sites across 6 countries: United States, Belgium, Colombia, Germany, Spain, Switzerland