Trials / Completed
CompletedNCT03377608
Modifiers of Tenofovir in the Female Genital Tract
Modifiers of Tenofovir Exposure in the Female Genital Tract of African Women on Depo-provera
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 50 (actual)
- Sponsor
- University of Minnesota · Academic / Other
- Sex
- Female
- Age
- 18 Years – 35 Years
- Healthy volunteers
- Not accepted
Summary
Two-armed, single visit, pharmacokinetic study to compare tenofovir diphosphate concentrations in cervical tissues of women on Depo-Provera contraception vs non-hormonal contraception.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Tenofovir Disoproxil Fumarate | Two cervical biopsies, blood plasma, PBMC, urine, and two cervicovaginal swabs will be collected at a single study visit |
| DRUG | Depo-Provera | Two cervical biopsies, blood plasma, PBMC, urine, and two cervicovaginal swabs will be collected at a single study visit |
Timeline
- Start date
- 2017-11-17
- Primary completion
- 2018-03-29
- Completion
- 2018-04-02
- First posted
- 2017-12-19
- Last updated
- 2018-05-01
Locations
1 site across 1 country: Uganda
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT03377608. Inclusion in this directory is not an endorsement.