NCT03376126

Minimally-Invasive Isolated Limb Perfusion

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 10 (estimated)
• Sponsor: Vastra Gotaland Region · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim is to analyse feasibility of a minimally-invasive isolated limb perfusion.

Detailed description

Isolated limb perfusion (ILP) and isolated limb infusion (ILI) are treatment options for patients with in-transit metastases of melanoma and locally advanced extremity sarcomas. There are several advantages for each method, but if the well-established effects of ILP could be combined to the minimally invasive approach of ILI, the results could be maximized and adverse events, related to open approach, minimized. A new method for vascular approach (MI-ILP) will be evaluated in a phase I feasibility study. Percutaneous vascular access of the ipsilateral side will be performed by ultrasound guided technique and connected to an extracorporeal oxygenation system. Perfusion will be conducted in the same way as for open ILP. Outcomes, technical details and complications will be recorded prospectively.

Conditions

• Isolated Limb Perfusion

Interventions

Type	Name	Description
OTHER	Minimal-invasive isolated limb perfusion	Minimal-invasive isolated limb perfusion

Timeline

• Start date: 2016-06-01
• Primary completion: 2024-12-31
• Completion: 2024-12-31
• First posted: 2017-12-18
• Last updated: 2024-01-26

Locations

1 site across 1 country: Sweden