Clinical Trials Directory

Trials / Completed

CompletedNCT03374540

Rivaroxaban vs Warfarin for SPAF in Multi-morbid Patients

Comparative Effectiveness of Rivaroxaban and Warfarin for Stroke Prevention in Multi-morbid Patients With Nonvalvular Atrial Fibrillation

Status
Completed
Phase
Study type
Observational
Enrollment
78,517 (actual)
Sponsor
Bayer · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The overall goal of this study was to evaluate the comparative safety and effectiveness of rivaroxaban vs. vitamin K antagonist (VKA) for stroke prevention in patients with nonvalvular atrial fibrillation (NVAF) across risk profiles and comorbidities that reflect everyday clinical practice. The primary objective in this study was to evaluate the combined end point of stroke or systemic embolism (SSE), and major bleeding in NVAF patients treated with rivaroxaban vs. VKA.

Conditions

Interventions

TypeNameDescription
DRUGRivaroxaban (Xarelto, BAY59-7939)15/20 mg
DRUGVitamin K antagonist (VKA)Individually adjusted dose

Timeline

Start date
2017-12-01
Primary completion
2019-08-30
Completion
2019-08-30
First posted
2017-12-15
Last updated
2020-08-17

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT03374540. Inclusion in this directory is not an endorsement.