NCT03374436

Impact of Sprint Stair Climbing "Snacks" on Markers of Metabolism and Vascular Function

Salivary Insulin Profiles Throughout the Day in Healthy Humans

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 23 (actual)
• Sponsor: University of British Columbia · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

Prolonged sitting has been shown to impair metabolism and vascular function. The overall purpose of this study is to determine if breaking up prolonged (9 hours) of sitting with brief (\~20 second) stair climbing exercise "snacks" can improve markers of metabolic control and vascular health in healthy young male participants and in males or females with overweight/obesity who are at risk of insulin resistance. An additional purpose is to determine if saliva insulin can be used as a valid indicator of blood insulin when measured throughout the day in sedentary and active conditions and when diets with different amounts of carbohydrates are consumed.

Conditions

• Physical Activity
• Diet Modification

Interventions

Type	Name	Description
BEHAVIORAL	High-Carbohydrate Sedentary	Three high-carbohydrate meals will be consumed (breakfast, lunch, and dinner) at \~3 hour intervals while participants remain in a seated position for the entire 9 hour intervention period.
BEHAVIORAL	High-Carbohydrate Active	Three high-carbohydrate meals will be consumed (breakfast, lunch, and dinner) at \~3 hour intervals while participants remain in a seated position for the entire 9 hour intervention period except that once every hour they will ascend three flights of stairs vigorously (stair climbing sprint "snack") for a total of 8 active breaks.
BEHAVIORAL	Low-carbohydrate Sedentary	Three low-carbohydrate meals will be consumed (breakfast, lunch, and dinner) at \~3 hour intervals while participants remain in a seated position for the entire 9 hour intervention period. This condition will provide a condition where the blood glucose and insulin responses are relatively low and stable throughout the day.

Timeline

• Start date: 2017-10-01
• Primary completion: 2019-06-30
• Completion: 2019-08-30
• First posted: 2017-12-15
• Last updated: 2019-09-25

Locations

1 site across 1 country: Canada